At around 1.30am on Monday 11th April, officers were called to reports that three males were breaking into John Bell Jewellers on Kings Street and items were stolen.
It was reported that the suspects drove off in a white Seat car towards Portland Street.
An investigation is now underway, and officers remain at the location today to continue with enquiries.
Detective Inspector Paul Gillies said: "Thankfully no one was hurt while the offenders rammed the front of the shop and carried out the burglary.
"At this early stage of the investigation we are looking for any information on the movement of the white Seat before and after this incident, as well as any suspicious activity in the area.
"If you were passing on foot or in a vehicle, and have any images, video or dashcam footage, get in touch as any small piece of evidence could be crucial to identifying those responsible and putting them before the courts.
"Likewise, if any individuals or businesses who are offered to buy any jewellery since the incident and have any suspicions where it came from then do the right thing and get in contact."
Please contact Merseyside Police's social media desk on Twitter Merseyside Police Contact Centre or Facebook ‘Merseyside Police Contact Centre’ with reference 22000246949 or call 101. You can also contact the independent charity Crimestoppers anonymously on 0800 555 111.